Diseases and Conditions

Primary sclerosing cholangitis

Risk factors

Factors that may increase the risk of primary sclerosing cholangitis include:

  • Age. Primary sclerosing cholangitis can occur at any age, but it's most often diagnosed between the ages of 30 and 40.
  • Sex. Primary sclerosing cholangitis occurs more often in men.
  • Inflammatory bowel disease. A large proportion of people with primary sclerosing cholangitis also have inflammatory bowel disease.
  • Geographical location. People with Northern European heritage have a higher risk of primary sclerosing cholangitis.

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